ALDH3B1

ALDH3B1
Tanımlayıcılar
Başka adlarALDH3B1
Dış kimliklerOMIM: 600466 MGI: 1914939 HomoloGene: 73890 GeneCards: ALDH3B1
Gen yerleşimi (İnsan)
11. Kromozom (insan)
Krom.11. Kromozom (insan)[1]
11. Kromozom (insan)
ALDH3B1 için genom yerleşimi
ALDH3B1 için genom yerleşimi
Bant11q13.2Başlangıç68,008,578 bç[1]
Bitiş68,029,282 bç[1]
Gen ontolojisi
Moleküler işlevi• 3-chloroallyl aldehyde dehydrogenase activity
• GO:0001948, GO:0016582 protein bağlanması
• oxidoreductase activity
• aldehyde dehydrogenase [NAD(P)+ activity]
• aldehyde dehydrogenase (NAD+) activity
• oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor
Hücresel bileşeni• Vezikül
• membrane
• Hücre zarı
• extracellular exosome
• secretory granule membrane
• specific granule membrane
• sitoplazma
• Sitozol
Biyolojik süreci• ethanol catabolic process
• lipid metabolism
• aldehyde catabolic process
• sphingolipid biosynthetic process
• cellular aldehyde metabolic process
• cellular response to oxidative stress
• Metabolizma
• alcohol metabolic process
• neutrophil degranulation
Kaynaklar:Amigo / QuickGO
Ortologlar
TürlerİnsanFare
Entrez

221

67689

Ensembl

ENSG00000006534

ENSMUSG00000024885

UniProt

P43353
Q9BUJ8

Q80VQ0

RefSeq (mRNA)

NM_001290059
NM_000694
NM_001030010
NM_001161473
NM_001290058

NM_026316

RefSeq (protein)

NP_000685
NP_001025181
NP_001154945
NP_001276987
NP_001276988

NP_080592

Yerleşim (UCSC)Krom. 11: 68.01 – 68.03 Mbn/a
PubMed araması[2][3]
Vikiveri
İnsan'ı Gör/DüzenleFare'yi Gör/Düzenle

Aldehit dehidrogenaz aile 3, üye B1, insanların 11. kromozomunda yer alan ALDH3B1 geni tarafından kodlanan bir enzimdir.[4][5]

Kaynakça

  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000006534 - Ensembl, May 2017
  2. ^ "İnsan PubMed Başvurusu:". National Center for Biotechnology Information, U.S. National Library of Medicine. Arşivlenmesi gereken bağlantıya sahip kaynak şablonu içeren maddeler (link)
  3. ^ "Fare PubMed Başvurusu:". National Center for Biotechnology Information, U.S. National Library of Medicine. Arşivlenmesi gereken bağlantıya sahip kaynak şablonu içeren maddeler (link)
  4. ^ Hsu LC, Chang WC, Yoshida A (Dec 1994). "Cloning of a cDNA encoding human ALDH7, a new member of the aldehyde dehydrogenase family". Gene. 151 (1–2). ss. 285-9. doi:10.1016/0378-1119(94)90672-6. PMID 7828891. 
  5. ^ Hsu LC, Chang WC, Yoshida A (Apr 1997). "Human aldehyde dehydrogenase genes, ALDH7 and ALDH8: genomic organization and gene structure comparison". Gene. 189 (1). ss. 89-94. doi:10.1016/S0378-1119(96)00839-6. PMID 9161417. 

Further reading

  • Sun X, Jia Y, Zhang X, Xu Q, Shen Y, Li Y (Jun 2005). "Multi-locus association study of schizophrenia susceptibility genes with a posterior probability method". Science in China Series C: Life Sciences. 48 (3). ss. 263-9. doi:10.1007/bf03183620. PMID 16092759. 
  • Hsu LC, Chang WC, Yoshida A (Dec 1994). "Cloning of a cDNA encoding human ALDH7, a new member of the aldehyde dehydrogenase family". Gene. 151 (1–2). ss. 285-9. doi:10.1016/0378-1119(94)90672-6. PMID 7828891. 
  • Marchitti SA, Orlicky DJ, Vasiliou V (May 2007). "Expression and initial characterization of human ALDH3B1". Biochemical and Biophysical Research Communications. 356 (3). ss. 792-8. doi:10.1016/j.bbrc.2007.03.046. PMC 1899873 $2. PMID 17382292. 
  • Saito A, Kawamoto M, Kamatani N (Jun 2009). "Association study between single-nucleotide polymorphisms in 199 drug-related genes and commonly measured quantitative traits of 752 healthy Japanese subjects". Journal of Human Genetics. 54 (6). ss. 317-23. doi:10.1038/jhg.2009.31. PMID 19343046. 
  • Wang Y, Hu Y, Fang Y, Zhang K, Yang H, Ma J, Xu Q, Shen Y (Jun 2009). "Evidence of epistasis between the catechol-O-methyltransferase and aldehyde dehydrogenase 3B1 genes in paranoid schizophrenia". Biological Psychiatry. 65 (12). ss. 1048-54. doi:10.1016/j.biopsych.2008.11.027. PMID 19159868. 
  • Yoshida A, Rzhetsky A, Hsu LC, Chang C (Feb 1998). "Human aldehyde dehydrogenase gene family". European Journal of Biochemistry. 251 (3). ss. 549-57. doi:10.1046/j.1432-1327.1998.2510549.x. PMID 9490025.