Eksoribonukleaza II

Eksoribonukleaza II
Identifikatori
EC broj3.1.13.1
CAS broj37288-24-7
Baze podataka
IntEnzIntEnz pregled
BRENDABRENDA pristup
ExPASyNiceZyme pregled
KEGGKEGG pristup
MetaCycmetabolički put
PRIAMprofil
Strukture PBPRCSB PDB PDBe PDBj PDBsum
Pretraga
PMCčlanci
PubMedčlanci
NCBIproteini

Eksoribonukleaza II (EC 3.1.13.1, ribonukleaza II, ribonukleaza Q, BN ribonukleaza, Escherichia coli ekso-RNaza II, RNaza II, eksoribonukleaza, 5'-eksoribonukleaza) je enzim sa sistematskim imenom '.[1][2][3][4] Ovaj enzim katalizuje sledeću hemijsku reakciju

Eksonukleolitičko razlaganje u 3'- ka 5'- smeru čime se formiraju nukleozid 5'-fosfati

Ova enzim preferentno deluje na jednolačanu DNK.

Reference

  1. ^ Nossal, N.G. & Singer, M. (1968). „The processive degradation of individual polyribonucleotide chains. I. Escherichia coli ribonuclease II”. J. Biol. Chem. 243: 913—922. PMID 4867942. 
  2. ^ Schmidt, F.J. & McClain, W.H. (1978). „An Escherichia coli ribonuclease which removes an extra nucleotide from a biosynthetic intermediate of bacteriophage T4 proline transfer RNA”. Nucleic Acids Res. 5: 4129—4139. PMID 364422. 
  3. ^ Shimura, Y., Sakano, H. and Nagawa, F. (1978). „Specific ribonucleases involved in processing of tRNA precursors of Escherichia coli. Partial purification and some properties”. Eur. J. Biochem. 86: 267—281. PMID 350582. CS1 одржавање: Вишеструка имена: списак аутора (веза)
  4. ^ Sporn, M.B., Lazarus, H.M. Smith, J.M. and Henderson, W.R. (1969). „Studies on nuclear exoribonucleases. 3. Isolation and properties of the enzyme from normal and malignant tissues of the mouse”. Biochemistry. 8: 1698—1706. PMID 5805304. CS1 одржавање: Вишеструка имена: списак аутора (веза)

Literatura

  • Nicholas C. Price; Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third изд.). USA: Oxford University Press. ISBN 019850229X. 
  • Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 изд.). Wiley-Interscience. ISBN 0471205036. 
  • Branden C; Tooze J. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN 0-8153-2305-0. 
  • Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 изд.). Wiley Classics Library. ISBN 0471303097. 

Spoljašnje veze

  • Exoribonuclease+II на US National Library of Medicine Medical Subject Headings (MeSH)
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TemeTipovi
  • B enzm: 1.1/2/3/4/5/6/7/8/10/11/13/14/15-18, 2.1/2/3/4/5/6/7/8, 2.7.10, 2.7.11-12, 3.1/2/3/4/5/6/7, 3.1.3.48, 3.4.21/22/23/24, 4.1/2/3/4/5/6, 5.1/2/3/4/99, 6.1-3/4/5-6
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