Perimyositis

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Medical condition

Perimyositis
Specialty	Rheumatology

Perimyositis is inflammation of the connective tissue around a muscle.^[1]

See also

myopathy (muscle disease)
myalgia (muscle pain)
Masticatory muscle myositis (a disease in dogs)
myositis

References

^ Serratrice, G.; Pellissier, J. F.; Roux, H.; Quilichini, P. (May 1990). "Fasciitis, perimyositis, myositis, polymyositis, and eosinophilia". Muscle & Nerve. 13 (5): 385–395. doi:10.1002/mus.880130505. ISSN 0148-639X. PMID 2189069. S2CID 37302966.

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Inflammation

Symptoms

Flushing (Rubor)
Fever (Calor)
Swelling (Tumor)
Pain (Dolor)
Loss of function (Functio laesa)

Mechanism

Acute

Plasma-derived mediators

Bradykinin
complement
- C3
- C5a
- MAC
coagulation

Cell-derived mediators

preformed	Lysosome granules biogenic amines Histamine Serotonin
synthesized on demand	cytokines IFN-γ IL-8 TNF-α IL-1 eicosanoids Leukotriene B4 Prostaglandins Nitric oxide Kinins

Other

Tests

General

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Systemic connective tissue disorders

General

Systemic lupus erythematosus	Drug-induced SLE Libman–Sacks endocarditis Lupus nephritis
Inflammatory myopathy	Myositis Dermatopolymyositis Dermatomyositis/Juvenile dermatomyositis Polymyositis* Inclusion body myositis
Scleroderma	Systemic scleroderma Progressive systemic sclerosis CREST syndrome
Overlap syndrome / Mixed connective tissue disease

Other hypersensitivity/autoimmune

Sjögren syndrome

Other

v t e Symptoms and conditions relating to muscle
Pain	Myalgia Fibromyalgia Acute Delayed onset
Inflammation	Myositis Pyomyositis Myoedema (Hypothyroid myopathy)
Destruction	Muscle weakness Rhabdomyolysis Muscle atrophy/Amyotrophy
Low ATP reservoir	Muscle fatigue Exercise intolerance Myogenic hyperuricemia Dynamic symptoms (exercise-induced) Inappropriate rapid heart rate response to exercise (tachycardia) Exaggerated cardiorespiratory response to exercise (tachycardia with tachypnea and/or hyperpnea (exercise hyperventilation)) Hitting the wall Second wind (Metabolic myopathies Diabetes Hypothyroid myopathy Hyperthyroid myopathy Hypoparathyroidism Hypokalemia Hypoxic muscle Pseudohypoxia Intermittent claudication Scurvy Fasting / Starvation Alcoholism)
Abnormal movement	Muscle cramp Myokymia Muscle spasm Fasciculations Muscle contracture Fibrosis Adhesion Myotonia Muscle channelopathies Pseudo-myotonia (Brody myopathy) Spasticity Rippling muscle disease Periodic paralysis Hypotonia / Hypertonia
Other	Myositis ossificans Fibrodysplasia ossificans progressiva Compartment syndrome Anterior Diastasis of muscle Diastasis recti Pseudoathletic appearance (Muscle hyperplasia / Muscle hypertrophy / Pseudohypertrophy)

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