Outer nuclear layer

Outer nuclear layer
Section of retina. (Outer nuclear layer labeled at right, fourth from the bottom.)
Plan of retinal neurons. (Outer nuclear layer labeled at left, third from the bottom.)
Details
Identifiers
Latin	stratum nucleare externum retinae
TA98	A15.2.04.012
FMA	58684
Anatomical terminology [edit on Wikidata]

The outer nuclear layer (or layer of outer granules or external nuclear layer), is one of the layers of the vertebrate retina, the light-detecting portion of the eye. Like the inner nuclear layer, the outer nuclear layer contains several strata of oval nuclear bodies; they are of two kinds, viz.: rod and cone granules, so named on account of their being respectively connected with the rods and cones of the next layer.

Rod granules

The spherical rod granules are much more numerous, and are placed at different levels throughout the layer.

Their nuclei present a peculiar cross-striped appearance, and prolonged from either extremity of each cell is a fine process; the outer process is continuous with a single rod of the layer of rods and cones; the inner ends in the outer plexiform layer in an enlarged extremity, and is imbedded in the tuft into which the outer processes of the rod bipolar cells break up.

In its course it presents numerous varicosities.

Cone granules

The stem-like cone granules, fewer in number than the rod granules, are placed close to the membrana limitans externa, through which they are continuous with the cones of the layer of rods and cones.

They do not present any cross-striation, but contain a pyriform nucleus, which almost completely fills the cell.

From the inner extremity of the granule a thick process passes into the outer plexiform layer, and there expands into a pyramidal enlargement or foot plate, from which are given off numerous fine fibrils, that come in contact with the outer processes of the cone bipolars.

References

This article incorporates text in the public domain from page 1016 of the 20th edition of Gray's Anatomy (1918)

External links

Histology image: 08008loa – Histology Learning System at Boston University
Histology image: 07902loa – Histology Learning System at Boston University

Anatomy of the globe of the human eye

Fibrous tunic
(outer)

Sclera	Episcleral layer Schlemm's canal Trabecular meshwork
Cornea	Limbus layers Epithelium Bowman's Stroma Dua's layer Descemet's Endothelium

Uvea / vascular
tunic (middle)

Choroid	Capillary lamina of choroid Bruch's membrane Sattler's layer
Ciliary body	Ciliary processes Ciliary muscle Pars plicata Pars plana
Iris	Stroma Pupil Iris dilator muscle Iris sphincter muscle

Retina (inner)

Layers	Inner limiting membrane Nerve fiber layer Ganglion cell layer Inner plexiform layer Inner nuclear layer Outer plexiform layer Outer nuclear layer External limiting membrane Layer of rods and cones Retinal pigment epithelium
Cells	Photoreceptor cells (Cone cell, Rod cell) → (Horizontal cell) → Bipolar cell → (Amacrine cell) → Retina ganglion cell (Midget cell, Parasol cell, Bistratified cell, Giant retina ganglion cells, Photosensitive ganglion cell) → Diencephalon: P cell, M cell, K cell, Muller glia
Other	Macula Perifoveal area Parafoveal area Fovea Foveal avascular zone Foveola Optic disc Optic cup Ora serrata

Anatomical regions
of the eye

Anterior segment	Adnexa (Eyebrow, Eyelid, Conjunctiva, Lacrimal system, Orbit) Fibrous tunic Anterior chamber Aqueous humour Iris Posterior chamber Ciliary body Lens Capsule of lens Zonule of Zinn
Posterior segment	Vitreous chamber Vitreous body Retina Choroid