KIF13B

Protein-coding gene in the species Homo sapiens
KIF13B
Available structures
PDBOrtholog search: PDBe RCSB
List of PDB id codes

2COW, 3FM8, 3GBJ, 3MDB

Identifiers
AliasesKIF13B, GAKIN, kinesin family member 13B
External IDsOMIM: 607350; MGI: 1098265; HomoloGene: 9073; GeneCards: KIF13B; OMA:KIF13B - orthologs
Gene location (Human)
Chromosome 8 (human)
Chr.Chromosome 8 (human)[1]
Chromosome 8 (human)
Genomic location for KIF13B
Genomic location for KIF13B
Band8p12Start29,067,278 bp[1]
End29,263,124 bp[1]
Gene location (Mouse)
Chromosome 14 (mouse)
Chr.Chromosome 14 (mouse)[2]
Chromosome 14 (mouse)
Genomic location for KIF13B
Genomic location for KIF13B
Band14|14 D1Start64,884,714 bp[2]
End65,047,066 bp[2]
RNA expression pattern
Bgee
HumanMouse (ortholog)
Top expressed in
  • olfactory bulb

  • corpus callosum

  • inferior ganglion of vagus nerve

  • internal globus pallidus

  • renal medulla

  • subthalamic nucleus

  • mucosa of ileum

  • medulla oblongata

  • C1 segment

  • sural nerve
Top expressed in
  • otolith organ

  • utricle

  • sciatic nerve

  • vestibular membrane of cochlear duct

  • aortic valve

  • ascending aorta

  • trigeminal ganglion

  • gastrula

  • left colon

  • lumbar subsegment of spinal cord
More reference expression data
BioGPS
n/a
Gene ontology
Molecular function
  • microtubule motor activity
  • nucleotide binding
  • microtubule binding
  • 14-3-3 protein binding
  • ATPase activity
  • protein binding
  • ATP binding
  • protein kinase binding
Cellular component
  • cytoplasm
  • cytosol
  • cell projection
  • kinesin complex
  • microvillus
  • axon
  • paranode region of axon
  • microtubule
  • cytoskeleton
Biological process
  • protein targeting
  • cytoskeleton-dependent intracellular transport
  • regulation of axonogenesis
  • microtubule-based movement
  • T cell activation
  • signal transduction
Sources:Amigo / QuickGO
Orthologs
SpeciesHumanMouse
Entrez

23303

16554

Ensembl

ENSG00000197892

ENSMUSG00000060012

UniProt

Q9NQT8

E9Q4K7

RefSeq (mRNA)

NM_015254

NM_001081177

RefSeq (protein)

NP_056069

NP_001074646

Location (UCSC)Chr 8: 29.07 – 29.26 MbChr 14: 64.88 – 65.05 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Kinesin family member 13B is a protein that in humans is encoded by the KIF13B gene. [5]

References

  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000197892 – Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000060012 – Ensembl, May 2017
  3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^ "Entrez Gene: Kinesin family member 13B". Retrieved 2016-09-01.

Further reading

  • Horiguchi K, Hanada T, Fukui Y, Chishti AH (2006). "Transport of PIP3 by GAKIN, a kinesin-3 family protein, regulates neuronal cell polarity". J. Cell Biol. 174 (3): 425–36. doi:10.1083/jcb.200604031. PMC 2064238. PMID 16864656.

External links

  • PDBe-KB provides an overview of all the structure information available in the PDB for Human Kinesin-like protein KIF13B


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